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MicroSort Clinical TrialAt Overlake Reproductive Health we are proud to be a west coast collaborator with the Genetics & IVF Institute, out of Fairfax Virginia, in the MicroSort clinical trial. MicroSort is a new scientific method designed to substantially increase the chance of a couple having a child of a particular gender. MicroSort is used before conception to separate sperm into those which produce girls (X-bearing sperm) or those that produce boys (Y-bearing sperm). At our clinic, the sorted sperm is frozen and then used with an in vitro fertilization (IVF) cycle. Couples wishing to use MicroSort for Family balancing must be married, have at least one child and want to sort for the less represented gender of children in the family. MicroSort can also be used for the prevention of X-linked diseases found in males but not females. Examples of such disorders are hemophilia or Duchene muscular dystrophy. How does MicroSort work? Sperm determine the sex of the child. Natural semen contains approximately equal numbers of female and male producing sperm. Microsort sperm separation produces a sample that has substantially changed proportions of X-bearing and Y-bearing sperm. This separation of female and male sperm is based on a measurable difference in quantity of their genetic material. The sorting technique separates the sperm in a machine called a flow cytometer. Based on animal and human studies, including over 400 offspring in several species over multiple generations, there appears to be no evidence to date that the flow cytometric method of sperm separation increases the rate of birth defects over what is expected in the general population. MicroSort is currently participating in a large clinical trial to more precisely define its safety and efficacy. Currently, Microsort X-bearing sperm separation for female gender selection is expected to make it 9 times more likely to have a girl that a boy. Microsort Y-bearing sperm separation for male gender selection is expected to make it 2-3 times more likely to have a boy that a girl. A child of the desired gender can not be guaranteed because the current technology does not completely exclude either female or male sperm cells form the enriched sample. As of October, 2000 over 100 babies have been born from this technology. Please visit Genetics & IVF institute's website at www.microsort.net to view the most recent data. To become a patient or for more information please call 1-425-646-4700,
please tell the receptionist that you are interested in the MicroSort
Program.
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